Serum lipid pattern in patients of liver cirrhosis


Abstract: Background: Cirrhosis is a complication of many liver diseases characterized by abnormal structure and function of the liver. Liver synthesizes the various lipoproteins involved in transporting cholesterol and lipids throughout the body. This makes liver an important site for lipid metabolism as well as its transport. Thus liver cirrhosis is associated with lipid abnormalities. Aim: To study lipid profile pattern in patients with cirrhosis. Materials and Methods: 30 patients with cirrhosis (cases) and 30 age and sex matched healthy patients (controls) were studied in the department of Biochemistry and central investigation laboratory in MGM Hospital, Aurangabad. Lipid profile (total, LDL, and HDL cholesterol and triglyceride) were done in both cases and control. Results were obtained by using statistical analysis. Results: In patients with liver cirrhosis, there was a significant decrease in lipid profile levels compared to the healthy control group (p<0.05). Conclusion: Dyslipidemia is a common finding in liver cirrhosis. Lipid profile should be adviced in all cases with liver cirrhosis.

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