Effect of hemodialysis on lung function in chronic renal failure A longitudinal study

Dr Selvarani C, Dr Pradeepa M

Background and Introduction: The most common cause of morbidity and mortality in developing countries are chronic diseases. Chronic renal failure (CRF) is one among the chronic diseases leading to a decreased quality of life. Chronic renal failure may eventually affect every system in the body including lungs due to acid-base imbalance. So this study was aimed to assess the pulmonary functions and also to study the effects of hemodialysis on lung function in chronic renal failure patients. Materials & Methods: 30 chronic renal failure patients in the age group of 45-60 years were selected for study group. The lung functions (FVC, FEV1, FEV1/FVC, FEF 25-75%) were carried out in these patients in predialysis and postdialysis period of 1day, 1week, 1month, 2months and 3months using spirometry. Cross sectional study was done. Results: The lung functions including VC, FVC, FEV1, PEF, FEF25-75% were significantly reduced in CRF patients but with regular hemodialysis for three months the values improved significantly(p value <0.05) but the values did not reach the level of the control group except FEV1%. The lung functions were significantly reduced in females when compared to males.

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